Rankings
| # | Player | Team | G | TKL▼ | Sk | QBH | INT | PD | FF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jordyn BrooksLB | MIA | 17 | 180 | 3.5 | 4 | 0 | 3 | 1 |
| 2 | Jack CampbellLB | DET | 17 | 174 | 5.0 | 5 | 0 | 4 | 3 |
| 3 | Devin WhiteLB | LV | 17 | 169 | 2.5 | 7 | 1 | 3 | 1 |
| 4 | Cedric GrayLB | TEN | 16 | 161 | 1.0 | 3 | 0 | 4 | 0 |
| 5 | Bobby WagnerMLB | WAS | 17 | 158 | 4.5 | 9 | 2 | 4 | 0 |
| 6 | Alex SingletonLB | DEN | 18 | 158 | 1.0 | 4 | 0 | 4 | 2 |
| 7 | Nate LandmanLB | LA | 20 | 156 | 2.5 | 5 | 1 | 8 | 5 |
| 8 | Jamien SherwoodLB | NYJ | 17 | 151 | 2.0 | 5 | 0 | 8 | 0 |
| 9 | Nick BoltonLB | KC | 17 | 150 | 1.0 | 7 | 1 | 6 | 1 |
| 10 | Ernest JonesLB | SEA | 18 | 149 | 0.5 | 1 | 6 | 8 | 1 |
| 11 | Foye OluokunLB | JAX | 18 | 147 | 1.0 | 2 | 1 | 11 | 2 |
| 12 | Kam CurlSAF | LA | 20 | 145 | 2.0 | 4 | 3 | 7 | 1 |
| 13 | Blake CashmanLB | MIN | 13 | 143 | 2.0 | 3 | 0 | 2 | 1 |
| 14 | Bobby OkerekeILB | NYG | 17 | 140 | 1.0 | 1 | 2 | 6 | 0 |
| 15 | Demario DavisOLB | NO | 17 | 140 | 0.5 | 2 | 0 | 3 | 2 |
| 16 | Payton WilsonLB | PIT | 18 | 129 | 2.0 | 4 | 1 | 3 | 0 |
| 17 | Patrick QueenLB | PIT | 18 | 129 | 1.0 | 5 | 0 | 4 | 1 |
| 18 | Roquan SmithILB | BAL | 15 | 128 | 0.0 | 4 | 0 | 3 | 0 |
| 19 | Zack BaunLB | PHI | 17 | 128 | 3.5 | 5 | 2 | 7 | 1 |
| 20 | Christian RozeboomLB | CAR | 16 | 128 | 2.0 | 2 | 1 | 4 | 1 |
| 21 | Tyrel DodsonLB | MIA | 16 | 127 | 5.0 | 6 | 1 | 3 | 1 |
| 22 | Edgerrin CooperLB | GB | 17 | 124 | 0.5 | 3 | 0 | 5 | 2 |
| 23 | Devin BushLB | CLE | 17 | 123 | 2.0 | 4 | 3 | 8 | 2 |
| 24 | Jordan BattleSAF | CIN | 17 | 123 | 0.0 | 0 | 4 | 6 | 2 |
| 25 | Zaire FranklinOLB | IND | 17 | 123 | 2.0 | 6 | 0 | 5 | 1 |
| 26 | Talanoa HufangaSAF | DEN | 19 | 122 | 2.0 | 3 | 0 | 13 | 1 |
| 27 | Tremaine EdmundsMLB | CHI | 15 | 121 | 1.0 | 3 | 4 | 10 | 0 |
| 28 | Dane BeltonSAF | NYG | 17 | 120 | 2.0 | 2 | 1 | 5 | 3 |
| 29 | Nick ScottSAF | CAR | 18 | 119 | 0.0 | 0 | 1 | 3 | 0 |
| 30 | Nick CrossSAF | IND | 17 | 118 | 2.5 | 6 | 1 | 5 | 1 |
| 31 | Chamarri ConnerDB | KC | 17 | 115 | 2.0 | 5 | 1 | 2 | 2 |
| 32 | Jeremy ChinnSAF | LV | 15 | 115 | 1.0 | 2 | 0 | 2 | 2 |
| 33 | Jaquan BriskerSAF | CHI | 19 | 114 | 2.0 | 4 | 1 | 10 | 0 |
| 34 | Daiyan HenleyLB | LAC | 17 | 114 | 3.5 | 6 | 3 | 6 | 0 |
| 35 | Craig WoodsonSAF | NE | 21 | 108 | 0.0 | 1 | 1 | 9 | 0 |
| 36 | Dee WintersLB | SF | 18 | 106 | 0.0 | 4 | 1 | 5 | 0 |
| 37 | Geno StoneSAF | CIN | 16 | 103 | 2.0 | 4 | 2 | 4 | 0 |
| 38 | Tre'von MoehrigSAF | CAR | 17 | 101 | 3.0 | 7 | 1 | 2 | 0 |
| 39 | Kevin ByardFS | CHI | 19 | 100 | 0.0 | 0 | 7 | 8 | 0 |
| 40 | Tykee SmithSAF | TB | 16 | 99 | 2.0 | 5 | 1 | 13 | 0 |
| 41 | Cole BishopSAF | BUF | 18 | 98 | 2.0 | 2 | 4 | 8 | 0 |
| 42 | Kamari LassiterCB | HOU | 18 | 97 | 0.0 | 1 | 4 | 21 | 0 |
| 43 | SirVocea DennisLB | TB | 16 | 96 | 3.0 | 7 | 1 | 5 | 0 |
| 44 | Kamren KinchensSAF | LA | 20 | 95 | 1.0 | 3 | 2 | 7 | 0 |
| 45 | Cooper DeJeanCB | PHI | 17 | 94 | 0.0 | 1 | 2 | 18 | 1 |
| 46 | Nick EmmanworiSAF | SEA | 17 | 93 | 2.5 | 4 | 1 | 15 | 0 |
| 47 | Devon WitherspoonCB | SEA | 15 | 89 | 1.5 | 7 | 1 | 11 | 0 |
| 48 | Christian GonzalezCB | NE | 18 | 87 | 1.0 | 0 | 1 | 17 | 1 |
| 49 | Riley MossCB | DEN | 19 | 86 | 1.0 | 1 | 1 | 19 | 0 |
| 50 | Marcus JonesCB | NE | 21 | 83 | 3.0 | 3 | 4 | 15 | 1 |