SF
San Francisco 49ers
NFC West·HC: Steve Mariucci
| Wk▲ | Date | Opp | Result | Spread | ATS | Total | O/U |
|---|---|---|---|---|---|---|---|
| 1 | Sep 12 | @ JAX | L 3-41 | +5.5 | ✗ | 49.0 / 44 | U |
| 2 | Sep 19 | NO | W 28-21 | -11.0 | ✗ | 42.5 / 49 | O |
| 3 | Sep 27 | @ ARI | W 24-10 | -2.5 | ✓ | 45.5 / 34 | U |
| 4 | Oct 3 | TEN | W 24-22 | -1.5 | ✓ | 40.5 / 46 | O |
| 5 | Oct 10 | @ STL | L 20-42 | +3.0 | ✗ | 45.5 / 62 | O |
| 6 | Oct 17 | CAR | L 29-31 | -5.0 | ✗ | 44.0 / 60 | O |
| 7 | Oct 24 | @ MIN | L 16-40 | +7.0 | ✗ | 48.5 / 56 | O |
| 9 | Nov 7 | PIT | L 6-27 | -2.5 | ✗ | 41.5 / 33 | U |
| 10 | Nov 14 | @ NO | L 6-24 | -1.0 | ✗ | 38.5 / 30 | U |
| 11 | Nov 21 | STL | L 7-23 | +7.5 | ✗ | 47.5 / 30 | U |
| 12 | Nov 29 | GB | L 3-20 | +6.0 | ✗ | 40.5 / 23 | U |
| 13 | Dec 5 | @ CIN | L 30-44 | +3.0 | ✗ | 39.0 / 74 | O |
| 14 | Dec 12 | ATL | W 26-7 | +3.0 | ✓ | 41.0 / 33 | U |
| 15 | Dec 18 | @ CAR | L 24-41 | +7.5 | ✗ | 46.0 / 65 | O |
| 16 | Dec 26 | WAS | L 20-26 | +7.0 | ✓ | 47.5 / 46 | U |
| 17 | Jan 3 | @ ATL | L 29-34 | +6.5 | ✓ | 46.5 / 63 | O |